The principal cytochrome P450 isoenzyme associated appears to get CYP2E1, with CYP1A2 and CYP3A4 as extra pathways. Close to 85% of the oral dose appears within the urine inside of 24 hrs of administration, most given that the glucuronide conjugate, with smaller quantities of other conjugates and unchanged drug (see OVERDOSAGE) for toxicity data.Do